Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Challenges in Patients with HIV/TB Coinfection

Open Forum Infect Dis; ePub 2018 Mar 21; Schechter, et al

Among persons with active tuberculosis (TB) coninfected with HIV, the majority had known HIV and were not on antiretroviral therapy (ART) prior to TB diagnosis, a recent study found. The retrospective cohort study included persons treated for culture-confirmed TB between 2008-2015 at an inner-city hospital in Atlanta, GA. Researchers found:

  • Among 274 persons with culture-confirmed TB, 96 (35%) had HIV coinfection, including 23 (24%) new HIV diagnoses and 73 (76%) previous diagnoses.
  • Among those with known HIV prior to TB, the median time of know HIV was 6 years with only 10 (14%) on ART at time of TB diagnosis.
  • 74 (81%) patients received SRT during treatment for TB and 47 (52%) had viral suppression (VS) at the end of TB treatment.
  • Only 32% of patients had continuous VS 3 years after completing TB treatment.

Citation:

Schechter MC, Bizune D, Kagei M, et al. Challenges across the HIV care continuum for patients with HIV/TB co-infection in Atlanta, GA. [Published online ahead of print March 21, 2018]. Open Forum Infect Dis. doi:10.1093/ofid/ofy063.

This Week's Must Reads

Difficult-to-Treat Resistance in GNBSIs, Clin Infect Dis; ePub 2018 Jul 23; Kadri, et al

Missed Opportunities for HIV Testing, Open Forum Infect Dis; ePub 2018 Jul 19; Kapadia, et al

Bacterial STI Screening Rates Among MSM, Sex Transm Dis; ePub 2018 Jul 24; Jenness, et al

Patient Engagement in HIV Care, AIDS; ePub 2018 Jul 12; Lee, Wu, et al

IDSA/ASM Lab Guide for Diagnosis of IDs, Clin Infect Dis; ePub 2018 Jun 28; Miller, et al

Must Reads in HIV

Missed Opportunities for HIV Testing, Open Forum Infect Dis; ePub 2018 Jul 19; Kapadia, et al

Syphilis Testing Among HIV-Positive MSM , Clin Infect Dis; ePub 2018 Jul 7; de Voux, et al

Predictors of Longitudinal PrEP Adherence Among MSM, J Infect Dis; ePub 2018 Jun 22; Pasipanodya, et al

Decreasing Incidence of SSTIs at US EDs, Clin Infect Dis; ePub 2018 Jun 15; Morgan, et al

Depressive Symptoms After ART Initiation, Clin Infect Dis; ePub 2018 Jun 12; Bengtson, et al