Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Socioeconomic Status & Risk of Infection & Sepsis

Clin Infect Dis; ePub 2018 Feb 12; Donnelly, et al

Higher neighborhood socioeconomic status (nSES) is associated with lower infection hospitalization rates, but there is no association with sepsis among those hospitalized. This according to a prospective cohort study using data from 30,239 participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study that examined the association between nSES and hospitalization for infection and sepsis. Infection and sepsis hospitalizations were identified from 2003-2012. Researchers found:

  • There were 3,054 hospitalizations for serious infection over a median follow-up of 6.5 years.
  • Infection incidence was lower for those in the highest nSES quartile vs the lowest quartile (11.7 vs 15.6 per 1,000 person-years); infections hazards were also lower for the highest quartile after adjustments for demographics, comorbidities, and functional status.
  • However, there was no association between nSES and sepsis among those hospitalized with infection.

Citation:

Donnelly JP, Lakkur S, Judd SE, et al. Association of neighborhood socioeconomic status with risk of infection and sepsis. [Published online ahead of print February 12, 2018]. Clin Infect Dis. doi:10.1093/cid/cix1109.

This Week's Must Reads

Disparities and Risk Factors for Septicemia Deaths , Open Forum Infect Dis; ePub 2018 Nov 15; Kempker, et al

Predicting Severe Outcomes in US Norovirus Outbreaks, J Infect Dis; ePub 2018 Nov 15; Burke, et al

RSV vs Influenza in Hospitalized Older Adults, Clin Infect Dis; ePub 2018 Nov 19; Ackerson, et al

Differences in HPV Seroprevalence By Sex, Clin Infect Dis; ePub 2018 Nov 24; Lewis, et al

Genital Wart Recurrence Among Unvaccinated Men, J Infect Dis; ePub 2018 Nov 2; Giuliano, et al

Must Reads in Healthcare-acquired Infections

Disparities and Risk Factors for Septicemia Deaths , Open Forum Infect Dis; ePub 2018 Nov 15; Kempker, et al

Predicting Severe Outcomes in US Norovirus Outbreaks, J Infect Dis; ePub 2018 Nov 15; Burke, et al

GI Microbiota Disruption with CRPA in ICU Patients, Clin Infect Dis; ePub 2018 Nov 1; Pettigrew, et al

Better Management of OPAT Can Reduce Readmissions, Clin Infect Dis; ePub 2018 Sep 21; Shah, et al

Low Plasma 25(OH)D and Risk of Sepsis, Open Forum Infect Dis; ePub 2018 Sep 18; Kempker, et al