In the US, outbreak-associated cases account for approximately 5% of all meningococcal disease cases, a recent study found. The retrospective review of all meningococcal disease cases reported from January 1, 2009 to December 31, 2013 was performed by state health departments and CDC to identify meningococcal disease outbreaks. An outbreak was defined as ≥2 primary cases of the same serogroup in <3 months in an organization, or an at-least 2-fold increase in disease rates in a community. Researchers found:
- From 2009 to 2013, 3,686 cases of meningococcal disease were reported in the US.
- Among these, 180 (4.9%) primary cases occurred as part of 36 outbreaks.
- Serogroup B was the primary cause of organization-based outbreaks.
- The majority of community-based outbreaks were due to serogroup C.
- Organization- and community-based outbreaks differed in predominant serogroup, age distribution of cases, and clinical syndrome.
Mbaeyi SA, Blain A, Whaley MJ, Wang X, Cohn AC, MacNeil JR. Epidemiology of meningococcal disease outbreaks in the United States, 2009–2013. [Published online ahead of print June 30, 2018]. Clin Infect Dis. doi:10.1093/cid/ciy548.
This Week's Must Reads
Disparities and Risk Factors for Septicemia Deaths , Open Forum Infect Dis; ePub 2018 Nov 15; Kempker, et al
Predicting Severe Outcomes in US Norovirus Outbreaks, J Infect Dis; ePub 2018 Nov 15; Burke, et al
RSV vs Influenza in Hospitalized Older Adults, Clin Infect Dis; ePub 2018 Nov 19; Ackerson, et al
Differences in HPV Seroprevalence By Sex, Clin Infect Dis; ePub 2018 Nov 24; Lewis, et al
Genital Wart Recurrence Among Unvaccinated Men, J Infect Dis; ePub 2018 Nov 2; Giuliano, et al
Must Reads in Emerging Infections
Meningococcal Disease Outbreaks in the US, Clin Infect Dis; ePub 2018 Jun 30; Mbaeyi, et al
Severe Respiratory Illness Linked to Rhinovirus, Clin Infect Dis; ePub 2017 Nov 23; Prill, et al
Seroreactivity to C6 Peptide in B. Miyamotoi Infections, Clin Infect Dis; ePub 2017 Nov 15; Molloy, et al
Regional Strategies to Limit Spread of CRE , Am J Infect Control; 2017 Nov 1; Gohil, et al
TB Diagnosis Among Foreign-Born Persons in the US, MMWR; ePub 2017 Mar 24; Tsang, Langer, et al