Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Weekend vs Weekday Leukemia Admissions

Clin Lymphoma Myeloma Leuk; ePub 2017 Aug 8; Parikh, et al

Patients with acute leukemia were more likely to experience hospital-mortality if they were admitted over the weekend vs during a weekday, according to a study involving nearly 83,000 leukemia admissions. Investigators identified participants diagnosed with leukemia using the 2002-2014 Nationwide Inpatient Sample, looking at weekend/weekday admissions and hospital-mortality. Among the results:

  • Overall, acute leukemia admissions declined by 22% in 2014 vs 2002.
  • In-hospital mortality declined from 19% to 15%.
  • 17% of admissions occurred over the weekend.
  • Hospital mortality rate was 19% among weekend admissions and 16% in those admitted during the week.
  • 28% of weekend admissions received early bone marrow biopsy, compared with 46% of those admitted during the week.
  • Patients who received bone marrow biopsy had 64% lower odds of hospital-mortality.
  • Those admitted to a teaching hospital had 35% lower odds of such.
  • Patients admitted over a weekend had 12% higher odds of hospital-mortality.
  • They were also more likely to experience complications (51% vs 48%).


Parikh K, Shah M, Mehta D, Arora S, Patel N, Liu Dx. Increased mortality among patients with acute leukemia admitted on weekends as compared to weekdays. [Published online ahead of print August 8, 2017]. Clin Lymphoma Myeloma Leuk. doi:10.1016/j.clml.2017.07.256.

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