Plasma Cell Disorders (part 3)
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Blood Cancer and BMT Program, Division of Hematology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO

Question 1 of 5

Questions 1 and 2 are based on the following case:

A 90-year-old woman is referred to your office after an elevated total protein level of 8.3 g/dL is found on routine blood testing. Serum calcium is 9.2 mg/dL, hemoglobin is 12.3 g/dL, and serum creatinine is 0.96 mg/dL. Radiologic testing shows no lytic skeletal lesions. Serum protein electrophoresis and immunofixation show an IgG-kappa M protein level of 0.2 g/dL. A 24-hour urine collection is negative for protein. Bone marrow biopsy shows 6% plasma cells (normal range 0–3%). She feels well and otherwise reports no symptoms.

What is this patient’s diagnosis?

Asymptomatic multiple myeloma

Light chain deposition disease

Monoclonal gammopathy of undetermined significance (MGUS)

Primary amyloidosis

Smoldering myeloma

Hospital Physician: Hematology/Oncology. 2019 February;14(2)

This quiz is not accredited for CME.

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