
Medical Intelligence Quiz
Challenge Yourself, Build Your Knowledge
Evans syndrome
Question 1 of 5
Topics
Quiz | |
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Fast Facts Friday: February 22, 2019 | Take Quiz |
Transformed indolent lymphoma and ASCT | Take Quiz |
Genes & AML | Take Quiz |
ALL outcomes in pediatric patients | Take Quiz |
Guideline updates for non-Hodgkin lymphomas: Part 2 | Take Quiz |
Guideline updates for non-Hodgkin lymphomas: Part 1 | Take Quiz |
Classification of adult ALL | Take Quiz |
HIV-related lymphomas and AHCT | Take Quiz |
Adult HL treatment | Take Quiz |
Diagnosis and assessment of ALL | Take Quiz |
Guideline updates for non-Hodgkin lymphomas: Part 3 | Take Quiz |
Staging of adult HL | Take Quiz |
Treatment of adult ALL | Take Quiz |
Screening & prevention of head & neck cancer | Take Quiz |
Prognosis of head & neck cancer | Take Quiz |
Epidemiology & risk factors associated with head & neck cancer | Take Quiz |
Diagnosis & staging of head & neck cancer | Take Quiz |
Diagnosis & management of infectious disease syndromes | Take Quiz |
Evaluation of a neutropenic patient with fever | Take Quiz |
Myelodysplastic syndrome | Take Quiz |
Therapeutic approaches to myelodysplastic syndrome | Take Quiz |
Fast Facts Friday
Fast Facts Friday
Quiz | |
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Fast Facts Friday: February 15, 2019 | Take Quiz |
Fast Facts Friday: February 8, 2019 | Take Quiz |
Fast Facts Friday: February 1, 2019 | Take Quiz |
Multiple Myeloma
Multiple Myeloma
Quiz | |
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Complications of multiple myeloma | Take Quiz |
Clinical progression from MGUS to multiple myeloma | Take Quiz |
Clinical evaluation of multiple myeloma | Take Quiz |
Outcomes of multiple myeloma | Take Quiz |
Pathogenesis of bone disease in multiple myeloma | Take Quiz |
Smoldering multiple myeloma | Take Quiz |
Relapsed and refractory multiple myeloma | Take Quiz |
Global burden of multiple myeloma | Take Quiz |
The relationship between obesity and multiple myeloma | Take Quiz |
Prognosis for multiple myeloma | Take Quiz |
ELOQUENT-3 trial: The addition of IgG monoclonal antibodies to treat multiple myeloma | Take Quiz |
Diagnostic intervals in multiple myeloma | Take Quiz |
Imaging techniques in multiple myeloma | Take Quiz |
Multiple myeloma signs, symptoms, and diagnosis | Take Quiz |
Pathophysiology of multiple myeloma | Take Quiz |
Pathological features of multiple myeloma | Take Quiz |
Staging multiple myeloma | Take Quiz |
Diagnostic criteria for multiple myeloma | Take Quiz |
Multiple myeloma: Diagnosis, staging, and risk stratification | Take Quiz |
Pathogenesis of multiple myeloma | Take Quiz |
Multiple myeloma: Epidemiology & features | Take Quiz |
Myeloma survival: Post-transplant response and minimal residual disease | Take Quiz |
Multiple myeloma outcomes: Lower- & higher-volume facilities | Take Quiz |
Multiple myeloma: MRD & survival | Take Quiz |
Smoldering multiple myeloma in the United States | Take Quiz |
Prognosis of multiple myeloma | Take Quiz |
Plasma cell neoplasms: The basics | Take Quiz |
Treatment of multiple myeloma | Take Quiz |
Plasma cell neoplasms: MGUS | Take Quiz |
Clinical features of multiple myeloma | Take Quiz |
Diagnosis and staging of multiple myeloma | Take Quiz |
Gynecologic Cancer
Gynecologic Cancer
Quiz | |
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Ovarian cancer risk factors | Take Quiz |
Incidence of ovarian cancer in the United States | Take Quiz |
Overview of ovarian cancer | Take Quiz |
USPSTF Recommendations: Cervical cancer screening | Take Quiz |
Uterine sarcoma treatment | Take Quiz |
Uterine sarcoma types & prognosis | Take Quiz |
Endometrial cancer risk, signs, and symptoms | Take Quiz |
Endometrial cancer: Prognostic factors | Take Quiz |
ASCO Guidelines: Primary prevention of cervical cancer | Take Quiz |
ASCO Guidelines: Cervical cancer screening | Take Quiz |
Subtypes of endometrial cancer | Take Quiz |
Screening & serum biomarkers for EOC | Take Quiz |
Prevention of EOC with RRSO | Take Quiz |
Diagnosis, evaluation, and treatment of EOC | Take Quiz |
Diagnosis & screening of endometrial cancer | Take Quiz |
Risk factors & screening for endometrial cancer | Take Quiz |
Prevention & screening of ovarian cancer | Take Quiz |
EOC pathology | Take Quiz |
Nodal spread & endometrial cancer | Take Quiz |
Renal Cell Carcinoma
Renal Cell Carcinoma
Quiz | |
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Imaging of metastatic renal cell carcinoma | Take Quiz |
Cytoreductive nephrectomy and lymphadenectomy in the management of kidney cancer | Take Quiz |
Renal cell carcinoma subtypes and imaging methods | Take Quiz |
Managing small renal masses, Part 2 | Take Quiz |
Managing small renal masses, Part 1 | Take Quiz |
Transitional cell cancer of the renal pelvis and ureter | Take Quiz |
Genetics of renal cell carcinoma | Take Quiz |
Clinical features of renal cell carcinoma | Take Quiz |
ASCO Guidelines: Management of renal cell masses | Take Quiz |
RCC subtypes: Risk factors, clinical findings, & imaging | Take Quiz |
Common RCC subtypes | Take Quiz |
AUA Guideline: Ablation procedures & RCC follow-up | Take Quiz |
AUA Guideline: RCC surgical follow-up & active surveillance | Take Quiz |
Staging & surveillance of RCC | Take Quiz |
Minimally invasive surgery for RCC | Take Quiz |
Pathophysiology & prognosis of RCC | Take Quiz |
Unique patient categories in RCC | Take Quiz |
Management of localized RCC | Take Quiz |
Sarcoma & GIST
Sarcoma & GIST
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Managing alveolar soft-part sarcoma | Take Quiz |
Alveolar soft-part sarcoma manifestation | Take Quiz |
Overview of Ewing sarcoma | Take Quiz |
Sarcoma: Importance of histology | Take Quiz |
Sarcoma imaging: STS or benign processes? | Take Quiz |
High-risk sarcomas & chemoradiation | Take Quiz |
Sarcoma: Radiotherapy benefits | Take Quiz |
Sarcoma: Radiation and surgical options | Take Quiz |
Stages of sarcoma | Take Quiz |
Diagnosing sarcoma | Take Quiz |
Sarcoma: Disease overview | Take Quiz |
Bleeding Disorders
Bleeding Disorders
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Evans syndrome | Take Quiz |
Serological findings in disseminated intravascular coagulation | Take Quiz |
Disseminated intravascular coagulation and cancer | Take Quiz |
Measuring fibrinolysis | Take Quiz |
Recent advances in the management of sickle cell disease | Take Quiz |
Current management of polycythemia vera & essential thrombocythemia | Take Quiz |
Update on the management of chronic neutrophilic leukemia | Take Quiz |
Transitioning from first-line therapies to treat immune thrombocytopenia | Take Quiz |
Solid organ transplantation for sickle cell disease | Take Quiz |
Factor V resistance to activated protein C | Take Quiz |
Pathophysiology of disseminated intravascular coagulopathy | Take Quiz |
Immunoglobulin A-associated vasculitis | Take Quiz |
Hematopoietic stem-cell transplantation for sickle-cell disease | Take Quiz |
Secondary iron overload | Take Quiz |
Characteristics of polycythemia vera | Take Quiz |
Diagnosis and treatment of immune thrombocytopenia | Take Quiz |
Pathophysiology of hemophilia | Take Quiz |
Hereditary hemorrhagic telangiectasia | Take Quiz |
Hypercoagulable states: Clinical features | Take Quiz |
Pancytopenia: Patient history & features | Take Quiz |
Sickle cell trait & HBA1c in African Americans | Take Quiz |
Hemophilia A and B: Characteristics & diagnosis | Take Quiz |
Sickle cell trait, rhabdomyolysis, and mortality | Take Quiz |
NHF Guideline: Hemophilia care models | Take Quiz |
Classification of von Willebrand disease | Take Quiz |
Treatment of von Willebrand disease | Take Quiz |
Pathophysiology of hemophilia A and B | Take Quiz |
Clinical manifestations of hemophilia | Take Quiz |
GVHD: Laboratory & imaging studies | Take Quiz |
Melanoma
Melanoma
Quiz | |
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BRAF wild-type advanced melanoma and checkpoint inhibitor efficacy | Take Quiz |
Uveal melanoma guidelines, Part 2 | Take Quiz |
Uveal melanoma guidelines, Part 1 | Take Quiz |
Childhood skin cancer | Take Quiz |
Etiology & clinical presentation of BCC | Take Quiz |
Etiology & presentation of squamous cell carcinoma | Take Quiz |
Uveal choroidal melanoma | Take Quiz |
Management of metastatic melanoma | Take Quiz |
Adjuvant treatment of melanoma | Take Quiz |
Melanoma early diagnosis and staging | Take Quiz |
Melanoma risk factors | Take Quiz |
Melanoma: Epidemiology & etiology | Take Quiz |
Clinical features of melanoma | Take Quiz |
Gastroenterology
Gastroenterology
Quiz | |
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Diagnosing metastatic gastric cancer | Take Quiz |
Overview of metastatic gastric cancer | Take Quiz |
Associations between pruritus, cancer, & race | Take Quiz |
Symptoms and treatment of stomach cancer | Take Quiz |
Management of pancreatic adenocarcinoma | Take Quiz |
Esophageal cancer symptoms, diagnosis, & prognosis | Take Quiz |
Hepatocellular carcinoma in liver transplant candidates | Take Quiz |
AASLD Guidelines: Treatment of hepatocellular carcinoma | Take Quiz |
ACS Guidelines: Colorectal cancer screening for average-risk adults | Take Quiz |
Hepatocellular carcinoma staging and treatment | Take Quiz |
Overview of gallbladder cancer | Take Quiz |
Etiology & treatment of anal cancer | Take Quiz |
Evaluating hepatocellular carcinoma | Take Quiz |
Treatment for GI carcinoid tumors | Take Quiz |
Treatment approaches for pancreatic cancer | Take Quiz |
Pancreatic cancer prognosis and overall survival | Take Quiz |
Diagnostics for GI carcinoids: Biochemical markers & imaging | Take Quiz |
HCC: Prognosis, diagnostic imaging & liver biopsy | Take Quiz |
Neuroendocrine tumors: Diagnosis | Take Quiz |
Pancreatic neuroendocrine tumors: Pathogenesis & prognostic factors | Take Quiz |
Colorectal cancer & endoscopic resection | Take Quiz |
USPSTF Guidelines: Update on CRC screening | Take Quiz |
Pathophysiology & prognosis of PDA | Take Quiz |
Staging, radiographic, & laboratory evaluation of PDA | Take Quiz |
Bowel preparation before colonoscopy | Take Quiz |
Bowel cleansing for colonoscopy: Diet, regimens, & rating | Take Quiz |
Colonoscopy surveillance after screening & polypectomy | Take Quiz |
Endoscopy in the staging & management of CRC | Take Quiz |
Head & Neck Cancers
Head & Neck Cancers
Quiz | |
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Risks in thyroid cancer management | Take Quiz |
Well-differentiated thyroid cancers | Take Quiz |
Types of primary malignant bone tumors | Take Quiz |
Oral cancer treatment and premalignant lesions | Take Quiz |
Risk and prevalence of oropharyngeal cancers | Take Quiz |
ATA Guidelines: Histopathologic evaluation of thyroidectomy samples in patients with DTC | Take Quiz |
ATA Guidelines: Secretory products & morphological examination of MTC | Take Quiz |
ATA Guidelines: Intraoperative voice and parathyroid management & follow-up in patients with DTC | Take Quiz |
ATA Guidelines: Voice and parathyroid issues in DTC | Take Quiz |
ATA Guidelines: Lymph node dissection & DTC | Take Quiz |
ATA Guidelines: Management of medullary thyroid | Take Quiz |
Thyroid cancer trends in the United States | Take Quiz |
DTC detection in obese and non-obese patients | Take Quiz |
Staging: Papillary & follicular thyroid cancer | Take Quiz |
Prognostic & risk factors of thyroid cancer | Take Quiz |
Thyroid nodules & thyroid metastases | Take Quiz |
Postoperative treatment of WDTC | Take Quiz |
Recurrent thyroid cancer | Take Quiz |
Thyroid gland malignancies: DTC, MTC, & ATC | Take Quiz |
Surgical treatment: Stage III & IV papillary & follicular thyroid cancer | Take Quiz |
The breast-thyroid cancer link | Take Quiz |
ATA Guidelines: Surgery for thyroid cancer | Take Quiz |
Impact of low iodine diet in DTC | Take Quiz |
ATA Guidelines: Preoperative neck ultrasound & laboratory tests for DTC | Take Quiz |
Epidemiology & clinical presentation of parathyroid carcinoma | Take Quiz |
Diagnosis & treatment of parathyroid carcinoma | Take Quiz |
Diagnosis & treatment of medullary thyroid cancer | Take Quiz |
Thyroid cancer outcomes | Take Quiz |
Clinical presentation & diagnosis of thyroid cancer | Take Quiz |
ATA Guidelines: Use of CT, MRI, and PET for neck imaging | Take Quiz |
ATA Guidelines: Initial management of DTC & neck imaging | Take Quiz |
Surgical treatment of primary stage differentiated thyroid cancer | Take Quiz |
Treatment of differentiated thyroid cancer | Take Quiz |
Types of differentiated thyroid cancer | Take Quiz |
Anemia
Anemia
Quiz | |
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Transplants for aplastic anemia treatment | Take Quiz |
Plasma volume and blood biomarkers | Take Quiz |
Features of aplastic anemia | Take Quiz |
Hypophosphatemia-associated stomatocytosis and anemia | Take Quiz |
Recent advances in the management of sickle cell disease | Take Quiz |
Opioid utilization patterns in individuals with sickle cell disease | Take Quiz |
Iron management in chemotherapy-induced anemia | Take Quiz |
Clinical phenotypes of sickle cell disease | Take Quiz |
Overview of hereditary stomatocytosis | Take Quiz |
Neurological complications in children with sickle cell | Take Quiz |
Etiology of sideroblastic anemia | Take Quiz |
Overview of beta-thalassemia | Take Quiz |
Overview of aplastic anemia | Take Quiz |
Overview of alpha thalassemia | Take Quiz |
Signs, symptoms, and staging of iron deficiency anemia | Take Quiz |
Pathophysiology of iron deficiency anemia | Take Quiz |
Alpha thalassemia: Management | Take Quiz |
Types of alpha thalassemia | Take Quiz |
Alpha thalassemia: Physical findings & diagnosis | Take Quiz |
Drug-induced hemolysis: Pathophysiology, diagnosis, & treatment | Take Quiz |
Prognosis & management of megaloblastic anemia | Take Quiz |
Acute complications of sickle cell disease | Take Quiz |
Chronic complications of sickle cell disease | Take Quiz |
Anemia in adults | Take Quiz |
Hydroxyurea & transfusion therapy in sickle cell disease | Take Quiz |
Anemia in children | Take Quiz |
Diagnosis of anemia | Take Quiz |
Mechanisms of anemia | Take Quiz |
Drug-induced hemolysis: Clinical features | Take Quiz |
Diagnosis of megaloblastic anemia | Take Quiz |
Immunotherapy
Immunotherapy
Quiz | |
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Checkpoint inhibition for cancer immunotherapy | Take Quiz |
Biomarkers for checkpoint inhibition in hematologic malignancies | Take Quiz |
Immunohistochemical markers in non-small cell lung carcinoma | Take Quiz |
Targeting cancer with the immune system | Take Quiz |
Biomarkers for immune checkpoint inhibition in lung cancer | Take Quiz |
Evaluating responses to immunotherapy | Take Quiz |
Immunopharmacogenomics towards personalized cancer immunotherapy | Take Quiz |
Tumor escape mechanisms and immunotherapy in NHL | Take Quiz |
Biomarkers for immune checkpoint inhibition therapy in melanoma | Take Quiz |
Immune checkpoint inhibitors and survival outcomes | Take Quiz |
Emerging biomarkers in immunotherapy | Take Quiz |
Cell-mediated therapy to target lymphoma | Take Quiz |
Developing predictive biomarkers for immunotherapy | Take Quiz |
Check-point inhibitors in immunotherapy | Take Quiz |
Selecting biomarkers for immunotherapy | Take Quiz |
Cancer tumor markers | Take Quiz |
Immune checkpoints & non-specific immunotherapies | Take Quiz |
Monoclonal antibodies, adoptive cell therapy, & cytokines | Take Quiz |
Targeting inhibitors of immune responses & nonspecific immunotherapy | Take Quiz |
Active specific immunotherapy | Take Quiz |
Cancer preventive & cancer treatment vaccines | Take Quiz |
Gene-expression profiling of tumors for immunotherapy | Take Quiz |
Non-specific cancer immunotherapies & adjuvants | Take Quiz |
Cancer cells & the immune system | Take Quiz |
Cancer treatment: Monoclonal antibodies | Take Quiz |
Forms of immunotherapy | Take Quiz |
Breast cancer: Emerging immunotherapy options | Take Quiz |
Immunotherapy & non-small cell lung cancer | Take Quiz |
Immune checkpoints & their inhibitors | Take Quiz |
Immune checkpoint inhibitors & tumors with mismatch repair deficiency | Take Quiz |
PD-based cancer immunotherapy | Take Quiz |
The role of TGF-beta in human cancer | Take Quiz |
Immune checkpoint blockade: Tumor interferon signaling | Take Quiz |
Efficacy of adoptive T-cell therapy | Take Quiz |
Targeting the necrosome for cancer therapy | Take Quiz |
Mechanisms involved in the tumor microenvironment | Take Quiz |
B-cell receptor CD4+ T cells in cancer immunotherapy | Take Quiz |
Improving T-cell potency via the CAR spacer | Take Quiz |
ROR gamma agonists & antitumor immunity | Take Quiz |
Role of B cell regulation in carcinogenesis | Take Quiz |
Cancer therapies: Vaccine adjuvants, Part 2 | Take Quiz |
Cancer therapies: Vaccine adjuvants, Part 1 | Take Quiz |
Validation of biomarkers to predict cancer immunotherapy response | Take Quiz |
Immune checkpoint modulators & immune cell therapy | Take Quiz |
Function of Hippo pathway kinases in cancer | Take Quiz |
Cancer immunotherapy: Immune checkpoint blockers | Take Quiz |
Cancer immunotherapy target: Wnt/β-catenin signaling in dendritic cells | Take Quiz |
Understanding oncolytic viruses | Take Quiz |
Cancer immunotherapy: Producer T cells – Part 2 | Take Quiz |
Cancer immunotherapy: Producer T cells – Part 1 | Take Quiz |
Cancer immunotherapy: Oncolytic viruses | Take Quiz |
Immune checkpoint blockade in cancer therapy | Take Quiz |
Cancer immunotherapy: Targeting microRNAs | Take Quiz |
Cancer immunotherapy: Role of Tcon & Treg | Take Quiz |
IL-24 in immunotherapy | Take Quiz |
Key omics modalities for precision oncology | Take Quiz |
CAR T cell therapy in cancer treatment | Take Quiz |
Categories of tumor antigens | Take Quiz |
Checkpoint blockade therapy: Immune monitoring assays | Take Quiz |
Principles of cancer immunotherapy | Take Quiz |
PD-1/PD-L1 immune checkpoint blockade therapy | Take Quiz |
Oncolytic viruses as immunotherapy | Take Quiz |
Approaches to cancer immunotherapy | Take Quiz |
Cancer immunotherapy mechanisms, advantages, & disadvantages | Take Quiz |
Immunotherapy in MIS CRC | Take Quiz |
Cancer immunotherapy: CAR design | Take Quiz |
Precision immunotherapy | Take Quiz |
Molecular mechanisms of immune avoidance | Take Quiz |
Immunotherapy for brain tumors | Take Quiz |
Adenosine in the tumor microenvironment | Take Quiz |
The role of TILs and MILs in cancer therapy | Take Quiz |
Leveraging the antigenic identity of tumors | Take Quiz |
Advances in cancer immunotherapy | Take Quiz |
Novel technologies for cancer immunotherapy | Take Quiz |
Understanding cancer immunology & immunotherapy | Take Quiz |
Personalized cancer immunotherapy: Novel immune monitoring | Take Quiz |
Understanding cancer immunotherapy | Take Quiz |
AML
AML
Quiz | |
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Aging-associated changes in the hematopoietic system | Take Quiz |
Leukemic transformation of myeloproliferative neoplasms | Take Quiz |
Pathophysiology of adult AML | Take Quiz |
FDA Approval: Oral small molecule inhibitor for AML patients | Take Quiz |
Remission and recurrence of adult AML | Take Quiz |
Treatment of neutropenia | Take Quiz |
Types of neutropenia | Take Quiz |
Neutropenia etiology | Take Quiz |
Clonal hematopoiesis & risk for therapy-related cancer | Take Quiz |
AML: Androgen maintenance therapy & survival | Take Quiz |
Leukemia: Survival after cord-blood transplant | Take Quiz |
Telomere length and delayed bone marrow recovery in pediatric AML | Take Quiz |
Extramedullary disease & AML survival | Take Quiz |
Myelodysplastic Syndrome
Myelodysplastic Syndrome
Quiz | |
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Aging-associated changes in the hematopoietic system | Take Quiz |
Managing Ph-positive acute lymphoblastic leukemia | Take Quiz |
Myelodysplastic syndrome: Diagnosis, risk-stratification, and management | Take Quiz |
Chronic myelomonocytic leukemia: Diagnosis & management | Take Quiz |
Myelodysplatic syndrome risk and survival | Take Quiz |
Etiology of sideroblastic anemia | Take Quiz |
Pathophysiology of myelodysplastic syndrome | Take Quiz |
Clonal hematopoiesis & risk for therapy-related cancer | Take Quiz |
Myelodysplastic syndrome: Genetic mutations & outcomes | Take Quiz |
Chronic myelomonocytic leukemia: Survival after transplant | Take Quiz |
Hodgkin Lymphoma
Hodgkin Lymphoma
Quiz | |
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Diagnosis of Hodgkin lymphoma | Take Quiz |
Hodgkin lymphoma risk and prognostic factors | Take Quiz |
Management of Hodgkin lymphoma | Take Quiz |
Pathophysiology of Hodgkin lymphoma | Take Quiz |
Genitourinary Cancer
Genitourinary Cancer
Quiz | |
---|---|
Prognostic factors of bladder cancer | Take Quiz |
Incidence and histopathology of bladder cancer | Take Quiz |
Clinical features and diagnosis of bladder cancer | Take Quiz |
Clinical features of urothelial carcinoma | Take Quiz |
Risk and prognosis of testicular cancer | Take Quiz |
Clinical features of testicular cancer | Take Quiz |
Diagnosis and treatment of prostate cancer | Take Quiz |
Prostate cancer in the US | Take Quiz |
ASCO/CCO Guidelines: Prostate cancer & brachytherapy | Take Quiz |
AUA-SUO Guidelines: BCG relapse & salvage regimens in bladder cancer | Take Quiz |
AUA-SUO Guidelines: TURBT/Repeat resection & intravesical therapy in bladder cancer | Take Quiz |
RCC subtypes: Risk factors, clinical findings, & imaging | Take Quiz |
AUA-SUO Guidelines: Urine markers & TURBT/Repeat resection in bladder cancer | Take Quiz |
Common RCC subtypes | Take Quiz |
AUA Guideline: Ablation procedures & RCC follow-up | Take Quiz |
Testicular cancer: Staging & risk stratification | Take Quiz |
AUA Guideline: RCC surgical follow-up & active surveillance | Take Quiz |
AHRQ Review: Management of renal masses & localized renal cancer | Take Quiz |
Understanding urethral cancer | Take Quiz |
Staging & surveillance of RCC | Take Quiz |
Minimally invasive surgery for RCC | Take Quiz |
Management of penile cancer | Take Quiz |
Pathophysiology & prognosis of RCC | Take Quiz |
Risk factors & clinical features of bladder cancer | Take Quiz |
Unique patient categories in RCC | Take Quiz |
Management of localized RCC | Take Quiz |
Serum tumor markers & testicular cancer | Take Quiz |
Epidemiology & risk factors associated with testicular cancer | Take Quiz |
AUA Guideline: Follow-up for clinically localized renal neoplasms | Take Quiz |
Clinical features and pathology of bladder cancer | Take Quiz |
Treatment options for stage I & II RCC | Take Quiz |
Treatment options for RCC | Take Quiz |
RCC tumor characterization: Laboratory & imaging studies | Take Quiz |
Genetic risk factors associated with RCC | Take Quiz |
RCC subtypes | Take Quiz |
Pathology & natural history of renal cancer | Take Quiz |
RCC: Links & risk factors | Take Quiz |
Clinical features & management of RCC | Take Quiz |
Epidemiology & etiology of RCC | Take Quiz |
Risk factors and pathology of prostate cancer | Take Quiz |
Prostate cancer: Disease detection | Take Quiz |
Diagnosis & prognosis of bladder cancer | Take Quiz |
Classification of renal cell cancer | Take Quiz |
Staging of testicular cancer | Take Quiz |
Risk factors & prostate cancer | Take Quiz |
ASCO/ACS: Prostate cancer survivorship care guidelines | Take Quiz |
Survival in advanced prostate cancer | Take Quiz |
Understanding bladder cancer | Take Quiz |
Treatment of prostate cancer | Take Quiz |
ALL
ALL
Quiz | |
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Organ involvement in Langerhans cell histiocytosis | Take Quiz |
Managing Ph-positive acute lymphoblastic leukemia | Take Quiz |
Guidelines: Diagnostic workup of acute leukemia | Take Quiz |
NCHS Report: Pediatric cancer rates | Take Quiz |
Ph-like ALL in adults | Take Quiz |
Acute leukemia: Epidemiology & pathophysiology | Take Quiz |
Clinical signs & symptoms of acute leukemia | Take Quiz |
Initial management & tumor lysis syndrome in acute leukemia | Take Quiz |
Indolent Lymphoma
Indolent Lymphoma
Quiz | |
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Breast implant-associated anaplastic large cell lymphoma | Take Quiz |
Pathogenesis of mantle cell lymphoma | Take Quiz |
Characteristics of splenic marginal zone lymphoma | Take Quiz |
Transformation of follicular lymphoma | Take Quiz |
Clinical features of chronic lymphocytic leukemia | Take Quiz |
Clinical features of mycosis fungoides and Sézary syndrome | Take Quiz |
Overview of mantle cell lymphoma | Take Quiz |
mSMART Guidelines: Diagnosis & causes of Waldenstrom macroglobulinemia | Take Quiz |
Overview of chronic lymphocytic leukemia | Take Quiz |
About Waldenstrom macroglobulinemia | Take Quiz |
Mycosis fungoides: Early stages & treatment | Take Quiz |
Nodal marginal zone lymphoma: Epidemiology & clinical presentation | Take Quiz |
Splenic marginal zone lymphoma: Features, diagnosis, & management | Take Quiz |
Indolent B-cell lymphoma: Autologous & allogeneic stem cell transplantation | Take Quiz |
Waldenström’s macroglobulinemia & stem cell transplantation | Take Quiz |
Characteristics across indolent NHL subtypes | Take Quiz |
Mycosis fungoides: Clinical presentation, prognosis, & survival | Take Quiz |
A subset of indolent lymphomas: Features & outcomes | Take Quiz |
Mass cytometry study of follicular lymphoma tumors reveals cellular characteristics | Take Quiz |
Cutaneous B-cell lymphoma: Epidemiology & diagnosis | Take Quiz |
Marginal zone lymphoma & primary cutaneous anaplastic large cell lymphoma | Take Quiz |
Indolent lymphoma subtypes: Marginal zone lymphoma | Take Quiz |
Indolent lymphoma subtypes: Lymphoplasmacytic lymphoma | Take Quiz |
Indolent lymphoma subtypes: Follicular lymphoma | Take Quiz |
Waldenström macroglobulinemia: Symptoms & criteria for treatment | Take Quiz |
Patient & Survivor Care
Patient & Survivor Care
Quiz | |
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Optimal pain management for patients with cancer | Take Quiz |
Opioids in cancer care | Take Quiz |
Planning end-of-life care in advanced cancer | Take Quiz |
Cachexia in cancer | Take Quiz |
Treatment of neutropenia | Take Quiz |
Types of neutropenia | Take Quiz |
Neutropenia etiology | Take Quiz |
HCT & non-HCT cancer survivors: Morbidity & mortality | Take Quiz |
ASCO Guidelines: Integrating palliative care | Take Quiz |
Cancer survivors: Medication use for anxiety & depression | Take Quiz |
Transfusion Medicine
Transfusion Medicine
Quiz | |
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Whole blood and irradiated blood products | Take Quiz |
Transfusion medicine and platelets | Take Quiz |
Platelet products in transfusion medicine | Take Quiz |
The source of hematopoietic stem cells | Take Quiz |
Bacterial contamination of platelets | Take Quiz |
ASCO Guideline Update: Platelet transfusion for patients with cancer | Take Quiz |
Secondary iron overload | Take Quiz |
Adverse effects of RBC transfusion | Take Quiz |
Plasma exchange in therapeutic apheresis | Take Quiz |
Therapeutic uses of cytapheresis | Take Quiz |
RBC transfusion | Take Quiz |
Cochrane Review: Red blood cell transfusion strategies | Take Quiz |
Platelet transfusion for GI bleeding in patients on antiplatelet agents | Take Quiz |
AABB Guidelines: RBC transfusion thresholds & storage | Take Quiz |
Transfusion: Age of blood & mortality | Take Quiz |
Breast Cancer
Breast Cancer
Quiz | |
---|---|
Early stage breast cancer | Take Quiz |
Breast cancer treatment during pregnancy | Take Quiz |
Breast cancer: Types of surgery | Take Quiz |
Circulating tumor cell clusters & metastatic breast cancer outcomes | Take Quiz |
Breast cancer with leptomeningeal metastasis: Characteristics & outcomes | Take Quiz |
De novo metastatic breast cancer: Occurrence & outcome by subtype | Take Quiz |
Metastatic breast cancer: Adapting to changes during treatment | Take Quiz |
ASCO Guidelines: Adjuvant therapy selection & early-stage breast cancer | Take Quiz |
HER2 overexpression | Take Quiz |
Breast cancer: Tissue diagnosis & imaging studies | Take Quiz |
Early & advanced breast cancer: Use of imaging in evaluation & follow-up | Take Quiz |
Breast cancer: Circulating tumor cells | Take Quiz |
Metastatic breast cancer with ESR1 mutation: Clinical management considerations | Take Quiz |
ASCO Guidelines: Endocrine therapy & HR-positive metastatic breast cancer | Take Quiz |
ASCO Guidelines: HR-positive breast cancer & adjuvant endocrine therapy | Take Quiz |
ASCO/SSO/ASTRO Consensus Guideline: Margins for breast-conserving surgery with WBRT in DCIS | Take Quiz |
ASCO Guidelines: Use of biomarkers to guide therapy in early-stage invasive BC--Part 2 | Take Quiz |
ASCO/CAP Guidelines: HER2 and FISH testing | Take Quiz |
Factors related to breast cancer surgery choices | Take Quiz |
Obesity & postmenopausal breast cancer risk | Take Quiz |
Breast conservation & neoadjuvant therapy | Take Quiz |
Oophorectomy & breast cancer | Take Quiz |
Preventive Care
Preventive Care
Quiz | |
---|---|
FDA Approval: Expanded use of Gardasil 9 | Take Quiz |
Thrombosis
Thrombosis
Quiz | |
---|---|
Measuring fibrinolysis | Take Quiz |
Pathophysiology of antiphospholipid syndrome | Take Quiz |
Current management of polycythemia vera & essential thrombocythemia | Take Quiz |
Clinical manifestations of cryoglobulinemia | Take Quiz |
Vitamin D and thrombosis in systemic lupus | Take Quiz |
Transitioning from first-line therapies to treat immune thrombocytopenia | Take Quiz |
Immunoglobulin A-associated vasculitis | Take Quiz |
Protein C deficiency | Take Quiz |
Characteristics of polycythemia vera | Take Quiz |
Diagnosis and treatment of immune thrombocytopenia | Take Quiz |
Characteristics of essential thrombocythemia | Take Quiz |
Pathogenesis of immune thrombocytopenia | Take Quiz |
ISTH Guidance Statement: Identifying & preventing VTE in pediatric cancer | Take Quiz |
Hypercoagulable states: Clinical features | Take Quiz |
ASH Guidelines: Subsequent management of ITP | Take Quiz |
ASH Guidelines: Initial management of immune thrombocytopenia | Take Quiz |
ASH Guidelines: Typical features & diagnosis of immune thrombocytopenia | Take Quiz |
Guideline: Antithrombotic therapy for VTE, Part 2 | Take Quiz |
Guideline: Antithrombotic therapy for VTE, Part 1 | Take Quiz |
Pediatrics
Pediatrics
Quiz | |
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Childhood skin cancer | Take Quiz |
Unusual cancers of childhood | Take Quiz |
Retinoblastoma treatment and survival | Take Quiz |
Clinical features of retinoblastoma | Take Quiz |
HIV
HIV
Quiz | |
---|---|
HIV: Diarrheal alimentary tract disease, Part 1 | Take Quiz |
Rare Diseases
Rare Diseases
Quiz | |
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Clinical features of thymoma and thymic carcinoma | Take Quiz |
Unusual cancers of childhood | Take Quiz |
Cellular classification of thymoma and thymic carcinoma | Take Quiz |
Overview of Ewing sarcoma | Take Quiz |
Adrenocortical carcinoma treatment | Take Quiz |
Treatment approaches for pancreatic cancer | Take Quiz |
Pancreatic cancer prognosis and overall survival | Take Quiz |
CNS/Brain Cancer
CNS/Brain Cancer
Quiz | |
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Primary CNS lymphoma pathophysiology | Take Quiz |
Pituitary tumors: Signs & symptoms | Take Quiz |
Types of gliomas | Take Quiz |
In the News: Glioblastoma | Take Quiz |
Neuro-oncology
Neuro-oncology
Quiz | |
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Primary CNS lymphoma pathophysiology | Take Quiz |
Diagnosis and treatment of pheochromocytoma | Take Quiz |
Clinical features of pheochromocytoma | Take Quiz |
CML
CML
Quiz | |
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Overview of chronic myelogenous leukemia | Take Quiz |
CML: TKI adherence | Take Quiz |
Clinical Guidelines
Clinical Guidelines
Quiz | |
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AASLD Guidelines: Treatment of hepatocellular carcinoma | Take Quiz |
ACS Guidelines: Colorectal cancer screening for average-risk adults | Take Quiz |
ASCO Guideline Update: Platelet transfusion for patients with cancer | Take Quiz |
CHEST Guidelines for lung cancer screening | Take Quiz |
ASCO Guidelines: Primary prevention of cervical cancer | Take Quiz |
ASCO/CCO Guidelines: Prostate cancer & brachytherapy | Take Quiz |
ASCO Guidelines: Cancer treatment & cardiac dysfunction risk | Take Quiz |
Cochrane Review: Red blood cell transfusion strategies | Take Quiz |
2017 ASCO Quality Symposium highlights | Take Quiz |
Guideline: Antithrombotic therapy for VTE, Part 2 | Take Quiz |
ASCO Guidelines: Management of renal cell masses | Take Quiz |
ATA Guidelines: Intraoperative voice and parathyroid management & follow-up in patients with DTC | Take Quiz |
ATA Guidelines: Voice and parathyroid issues in DTC | Take Quiz |
ASCO Guidelines: Integrating palliative care | Take Quiz |
ATA Guidelines: Lymph node dissection & DTC | Take Quiz |
ASCO Guidelines: Cervical cancer screening | Take Quiz |
ASBMT Guidelines: Autologous progenitor cell transplant | Take Quiz |
AABB Guidelines: RBC transfusion thresholds & storage | Take Quiz |
AUA-SUO Guidelines: BCG relapse & salvage regimens in bladder cancer | Take Quiz |
AUA-SUO Guidelines: TURBT/Repeat resection & intravesical therapy in bladder cancer | Take Quiz |
ASBMT Guidelines: Autologous & allogeneic HCT considerations in special populations & comorbidities | Take Quiz |
AUA-SUO Guidelines: Urine markers & TURBT/Repeat resection in bladder cancer | Take Quiz |
ASBMT Guidelines: Allogeneic progenitor cell transplant | Take Quiz |
Common RCC subtypes | Take Quiz |
AUA-SUO Guidelines: Diagnosis of non-muscle invasive bladder cancer | Take Quiz |
ASCO Guidelines: Adjuvant therapy selection & early-stage breast cancer | Take Quiz |
AUA Guideline: Ablation procedures & RCC follow-up | Take Quiz |
NHF Guideline: Hemophilia care models | Take Quiz |
Acute complications of sickle cell disease | Take Quiz |
Chronic complications of sickle cell disease | Take Quiz |
Hydroxyurea & transfusion therapy in sickle cell disease | Take Quiz |
ASCO Guidelines: Endocrine therapy & HR-positive metastatic breast cancer | Take Quiz |
ASCO Guidelines: HR-positive breast cancer & adjuvant endocrine therapy | Take Quiz |
ASCO/SSO/ASTRO Consensus Guideline: Margins for breast-conserving surgery with WBRT in DCIS | Take Quiz |
AUA Guideline: RCC surgical follow-up & active surveillance | Take Quiz |
ASCO Guidelines: Use of biomarkers to guide therapy in early-stage invasive BC--Part 2 | Take Quiz |
AUA Guideline: Follow-up for clinically localized renal neoplasms | Take Quiz |
ATA Guidelines: Surgery for thyroid cancer | Take Quiz |
ATA Guidelines: Preoperative neck ultrasound & laboratory tests for DTC | Take Quiz |
ATA Guidelines: Use of CT, MRI, and PET for neck imaging | Take Quiz |
ATA Guidelines: Initial management of DTC & neck imaging | Take Quiz |
Bowel preparation before colonoscopy | Take Quiz |
Bowel cleansing for colonoscopy: Diet, regimens, & rating | Take Quiz |
Colonoscopy surveillance after screening & polypectomy | Take Quiz |
Endoscopy in the staging & management of CRC | Take Quiz |
Risk factors & prostate cancer | Take Quiz |
ASCO/ACS: Prostate cancer survivorship care guidelines | Take Quiz |
Practice Management
Practice Management
Quiz | |
---|---|
Cancer estimates & incidence, 2018 | Take Quiz |
Principles of nutrition in cancer | Take Quiz |
Oncology
Oncology
Quiz | |
---|---|
ACS Guidelines: Colorectal cancer screening for average-risk adults | Take Quiz |
CHEST Guidelines for lung cancer screening | Take Quiz |
Active specific immunotherapy | Take Quiz |
ASCO Guidelines: Primary prevention of cervical cancer | Take Quiz |
ASCO/CCO Guidelines: Prostate cancer & brachytherapy | Take Quiz |
NSCLC: Delayed chemo & survival after surgery | Take Quiz |
ASCO Guidelines: Cancer treatment & cardiac dysfunction risk | Take Quiz |
PD-based cancer immunotherapy | Take Quiz |
Lung cancer: The role of imaging studies & chest CT | Take Quiz |
2017 ASCO Quality Symposium highlights | Take Quiz |
USPSTF Guidelines: Update on CRC screening | Take Quiz |
ASCO Guidelines: Management of renal cell masses | Take Quiz |
ASCO Guidelines: Integrating palliative care | Take Quiz |
ATA Guidelines: Lymph node dissection & DTC | Take Quiz |
ASCO Guidelines: Cervical cancer screening | Take Quiz |
AUA-SUO Guidelines: BCG relapse & salvage regimens in bladder cancer | Take Quiz |
AUA-SUO Guidelines: TURBT/Repeat resection & intravesical therapy in bladder cancer | Take Quiz |
AUA-SUO Guidelines: Urine markers & TURBT/Repeat resection in bladder cancer | Take Quiz |
Common RCC subtypes | Take Quiz |
AUA-SUO Guidelines: Diagnosis of non-muscle invasive bladder cancer | Take Quiz |
ASCO Guidelines: Adjuvant therapy selection & early-stage breast cancer | Take Quiz |
AUA Guideline: Ablation procedures & RCC follow-up | Take Quiz |
ASCO Guidelines: Endocrine therapy & HR-positive metastatic breast cancer | Take Quiz |
ASCO Guidelines: HR-positive breast cancer & adjuvant endocrine therapy | Take Quiz |
ASCO/SSO/ASTRO Consensus Guideline: Margins for breast-conserving surgery with WBRT in DCIS | Take Quiz |
AUA Guideline: RCC surgical follow-up & active surveillance | Take Quiz |
ASCO Guidelines: Use of biomarkers to guide therapy in early-stage invasive BC--Part 2 | Take Quiz |
AUA Guideline: Follow-up for clinically localized renal neoplasms | Take Quiz |
ATA Guidelines: Surgery for thyroid cancer | Take Quiz |
ATA Guidelines: Preoperative neck ultrasound & laboratory tests for DTC | Take Quiz |
ATA Guidelines: Use of CT, MRI, and PET for neck imaging | Take Quiz |
ATA Guidelines: Initial management of DTC & neck imaging | Take Quiz |
Bowel preparation before colonoscopy | Take Quiz |
Bowel cleansing for colonoscopy: Diet, regimens, & rating | Take Quiz |
Colonoscopy surveillance after screening & polypectomy | Take Quiz |
Endoscopy in the staging & management of CRC | Take Quiz |
Risk factors & prostate cancer | Take Quiz |
ASCO/ACS: Prostate cancer survivorship care guidelines | Take Quiz |
Hematology
Hematology
Quiz | |
---|---|
ASCO Guideline Update: Platelet transfusion for patients with cancer | Take Quiz |
Cochrane Review: Red blood cell transfusion strategies | Take Quiz |
Guideline: Antithrombotic therapy for VTE, Part 2 | Take Quiz |
ASBMT Guidelines: Autologous progenitor cell transplant | Take Quiz |
AABB Guidelines: RBC transfusion thresholds & storage | Take Quiz |
ASBMT Guidelines: Autologous & allogeneic HCT considerations in special populations & comorbidities | Take Quiz |
ASBMT Guidelines: Allogeneic progenitor cell transplant | Take Quiz |
NHF Guideline: Hemophilia care models | Take Quiz |
Cellular Therapy
Cellular Therapy
Quiz | |
---|---|
Solid organ transplantation for sickle cell disease | Take Quiz |
Hematopoietic stem-cell transplantation for sickle-cell disease | Take Quiz |
Hematopoietic stem cell transplantation | Take Quiz |
Rosai-Dorfman disease | Take Quiz |
Prognostic value of hematopoietic cell transplant comorbidity index | Take Quiz |
Myelodysplastic syndrome: Genetic mutations & outcomes | Take Quiz |
HSC donors & health-related quality of life | Take Quiz |
HSCT outcomes & vancomycin-resistant enterococcus colonization & bacteremia | Take Quiz |
Double-hit lymphomas: Outcomes after ASCT | Take Quiz |
Lung Cancer
Lung Cancer
Quiz | |
---|---|
CHEST Guidelines for lung cancer screening | Take Quiz |
NSCLC: Delayed chemo & survival after surgery | Take Quiz |
EGFR tyrosine kinase inhibition and lung cancer | Take Quiz |
Lung cancer: The role of imaging studies & chest CT | Take Quiz |
Understanding lung cancer | Take Quiz |
Advanced & previously treated NSCLC: The OAK & POPLAR trials by Bobby Daly, MD, MBA | Take Quiz |
PD-L1-Positive NSCLC and KEYNOTE-024, by Bobby Daly, MD, MBA | Take Quiz |
Pathology & clinical presentation of small cell lung cancer | Take Quiz |
Staging & imaging of small cell lung cancer | Take Quiz |
Treatment of stage IIIA NSCLCs | Take Quiz |
RAS mutations in NSCLC by Kevin Wood, MD | Take Quiz |
Treatment of early-stage NSCLCs | Take Quiz |
Clinical evaluation of single pulmonary nodules | Take Quiz |
NSCLC risk and subtypes | Take Quiz |
Lung cancer pathology | Take Quiz |
Nonmelanoma Skin Cancer
Nonmelanoma Skin Cancer
Quiz | |
---|---|
Merkel cell carcinoma treatment | Take Quiz |
Merkel cell carcinoma pathogenesis | Take Quiz |
First FDA-approved Merkel cell carcinoma treatment | Take Quiz |
T Cell Lymphomas
T Cell Lymphomas
Quiz | |
---|---|
Lymphocytopenia: Signs & symptoms, diagnosis, & treatment | Take Quiz |
Physical findings of mycosis fungoides | Take Quiz |
GI Oncology
GI Oncology
Quiz | |
---|---|
Pancreatic neuroendocrine tumors: Pathogenesis & prognostic factors | Take Quiz |
Colorectal cancer & endoscopic resection | Take Quiz |
USPSTF Guidelines: Update on CRC screening | Take Quiz |
Risk factors & screening for gastric cancers | Take Quiz |
Risk factors associated with PDA | Take Quiz |
Diagnostic laparoscopy & management of PDA | Take Quiz |
Management of PDA & metastatic disease | Take Quiz |
Treatment of esophageal cancer | Take Quiz |
Pathology & staging workup of esophageal cancer | Take Quiz |
Diagnosing PDA: Imaging & aspiration/biopsy | Take Quiz |
Clinical presentation & diagnosis of esophageal cancer | Take Quiz |
Epidemiology & etiology of esophageal cancer | Take Quiz |
Gastric cancer prevention | Take Quiz |
Rectal cancer: Neoadjuvant therapy vs surgery | Take Quiz |
Adenoma detection rates in CRC | Take Quiz |
Preoperative chemotherapy & colorectal cancer | Take Quiz |
Familial adenomatous polyposis & CRC | Take Quiz |
Screening of CRC | Take Quiz |
Colonoscopy: Optimizing adequate bowel cleansing | Take Quiz |
ASCO Guidelines: Surveillance protocol for survivors of CRC | Take Quiz |
Epidemiology & risk factors of CRC | Take Quiz |
Genetic evaluation & management of Lynch syndrome | Take Quiz |
Laparoscopic resection vs surgery for rectal cancer | Take Quiz |
Risk factors & prognosis of rectal cancer | Take Quiz |
Understanding hereditary CRC syndromes: Part 2 | Take Quiz |
Colorectal cancer screening: Flexible sigmoidoscopy | Take Quiz |
Aggressive Lymphomas
Aggressive Lymphomas
Quiz | |
---|---|
Double-hit lymphomas: Outcomes after ASCT | Take Quiz |
HCV: Increased non-Hodgkin lymphoma risk? | Take Quiz |
Non-Hodgkin lymphoma risk & HIV-Hepatitis coinfection | Take Quiz |
CLL
CLL
Quiz | |
---|---|
CLL & minimal residual disease status | Take Quiz |
CLL, genetic aberrations, & the elderly | Take Quiz |
Molecular prognostic indicators in CLL | Take Quiz |
CLL management & prognosis | Take Quiz |
Diagnosis, classification, & prognostic factors of CLL | Take Quiz |
CLL: Risk factors & prognostic factors | Take Quiz |
Staging CLL | Take Quiz |
Treatment of CLL | Take Quiz |
Understanding CLL | Take Quiz |
CLL: Risk factors & epidemiology | Take Quiz |
Understanding familial CLL | Take Quiz |
Clinical manifestations of CLL | Take Quiz |
Diagnosis of CLL | Take Quiz |
Case-Based Quizzes
Case-Based Quizzes
Quiz | |
---|---|
Advanced & previously treated NSCLC: The OAK & POPLAR trials by Bobby Daly, MD, MBA | Take Quiz |
PD-L1-Positive NSCLC and KEYNOTE-024, by Bobby Daly, MD, MBA | Take Quiz |
Metastatic Breast Cancer
Metastatic Breast Cancer
Quiz | |
---|---|
De novo metastatic breast cancer: Occurrence & outcome by subtype | Take Quiz |
Metastatic breast cancer: Adapting to changes during treatment | Take Quiz |
Metastatic breast cancer with ESR1 mutation: Clinical management considerations | Take Quiz |
ASCO Guidelines: Endocrine therapy & HR-positive metastatic breast cancer | Take Quiz |
Mantle Cell Lymphoma
Mantle Cell Lymphoma
Quiz | |
---|---|
MCL: Epidemiology, subtypes, & diagnosis | Take Quiz |
MCL: Diagnosis, treatment, & prognosis | Take Quiz |
Lymphoma & Plasma Cell Disorders
Lymphoma & Plasma Cell Disorders
Quiz | |
---|---|
Treatment of adult HL | Take Quiz |
Diagnosis & pathogenesis of primary CNS lymphoma | Take Quiz |
Indolent & aggressive NHL | Take Quiz |
Cellular classification & treatment of NHL | Take Quiz |
Understanding NHL | Take Quiz |
Prognosis of primary CNS lymphoma | Take Quiz |
Leukemia, Myelodysplasia, Transplantation
Leukemia, Myelodysplasia, Transplantation
Quiz | |
---|---|
Testing & mutational analysis in chronic myeloid leukemia | Take Quiz |