Hard Questions


Many people with metastatic cancer say they wouldn’t want invasive treatment near the end of life. But how do we know when it’s the end?

Hard Questions

Information overload

Once a patient hears “cancer,” they often stop listening. We could go on, spelling out the next steps and treatment options. But patients usually...

From the Editor

Pathologic superstition

Without certainty, how can a physician debunk a superstition?



Heroes change with the times and are metaphors for the real-life challenges we face and our abilities to overcome them.

Hard Questions

The oncologist’s dilemma

What do you do when the evidence doesn’t line up with the patient’s wishes?

From the Editor

Full disclosure

Dr. Matt Kalaycio thought he was free of financial conflicts because he doesn’t take pharma money. Then he checked Open Payments.


Slowing down

This past Labor Day weekend, I did something radical. I slowed down. Way down.

Hard Questions

When is the right time to stop treatment?

Patients often face a trade-off of more suffering with a small chance at remission, versus accepting no chance of cure but feeling well for as...


The impact of tuition-free medical education

This bold initiative, they stated, was being instituted to simultaneously address the rising costs of medical education while still attracting the...


A new way to classify endometrial cancer

If researchers can better define patients’ endometrial cancer at the time of their biopsy, important clinical decisions might be able to be...