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This Newly-Tested Tool Predicts PICC-DVT Risk

J Thromb Haemost; ePub 2017 Sep 13; Chopra, et al

A newly-tested tool can estimate the risk of deep vein thrombosis (DVT) in patients with peripherally inserted central catheters (PICCs), according to a study involving more than 23,000 individuals. Participants with upper extremity DVT were divided into 4 risk classes. The Michigan PICC-DVT Risk Score was then tested and validated to determine factors linked with PICC-DVT. Among the results:

  • 2% of patients developed PICC-DVT.
  • Risk factors included DVT history, multi-lumen PICC, active cancer, presence of another central venous catheter, and white blood cell count >12,000.
  • Thrombosis rates were 0.9% for class I, 1.6% for class II, 2.7% for class III, and 4.7% for class IV.
  • Predicted probabilities were 0.9%, 1.5%, 2.6%, and 4.5%, respectively.
  • Patients in class II were 50% more likely to develop PICC-DVT than those in class I.
  • Patients in classes III and IV were nearly 3 and >5 times more likely, respectively.


Chopra V, Kaatz S, Conlon A, et al. The Michigan Risk Score to predict peripherally inserted central catheter-associated thrombosis. [Published online ahead of print September 13, 2017]. J Thromb Haemost. doi:10.1111/jth.13794.