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One-fourth of placebo arm experience adverse events in RCC trials

Chacón M et al. JAMA Network Open. 2018 Dec 7. doi: 10.1001/jamanetworkopen.2018.5617

Key clinical point: Serious adverse events can occur in patients treated only with placebo in cancer clinical trials.

Major finding: The incidence of grade 3-4 placebo adverse events was 18% in cancer clinical trials.

Study details: Systematic review and meta-analysis of 10 randomized, placebo-controlled, double-blind trials.

Disclosures: No conflicts of interest were declared.

Read the article here.

Citation:

Chacón M et al. JAMA Network Open. 2018 Dec 7. doi: 10.1001/jamanetworkopen.2018.5617.