Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Survey indicates opioid prescriptions have decreased

Physicians' progress to reverse the nation's opioid epidemic. American Medical Association.

Key clinical point: Prescriptions for opioids decreased by 22% over the last 5 years and did so in all 50 states.

Major finding: Providers dispensed almost 56 million fewer opioid prescriptions in 2017 than they did in 2013. The total number of prescriptions fell from a total of nearly 252 million in 2013 to 196 million in 2017.

Study details: The number of health care professionals registered for prescription drug monitoring programs more than tripled as well.

Read the article.

This Week's Must Reads

Case studies shed light on treatment for rare form of MCL , Mori S et al. Clin Lymphoma Myeloma Leuk. 2019 Feb;19(2):e93-7.

Histopathological clues for differentiating follicular lymphomas, Servitje O et al. J Cutan Pathol. 2019;46:182-9.

Single agent daratumumab is not an option in B-cell lymphomas, Salles G et al. Clin Lymphoma Myeloma Leuk. 2019 Jan 2. doi: 10.1016/j.clml.2018.12.013.

Ibrutinib combo advances in CNS lymphoma, Grommes C et al. Blood. 2019;133(5):436-45.

Best frontline options for advanced follicular lymphoma, Shah NN et al. Clin Lymphoma Myeloma Leuk. 2019 Feb;19(2):95-102.

Must Reads in Practice Management

Over half of Americans support Medicare for All, Kaiser Family Foundation Health Tracking Poll – January 2019

No difference in financial distress with counseling intervention , Kircher SM et al. J Oncol Pract. 2019 Jan 9. doi: 10.1200/JOP.18.00270.

Many believe tumor profiling will benefit present treatment, Marron et al. JCO Precis Oncol. 2019 Jan 22. doi: 10.1200/PO.18.00176.

Physician mothers with extra caregiving at home at higher risk, Yank V et al. JAMA Internal Medicine. 2018 Jan 28. doi: 10.1001/jamainternmed.2018.6411.