Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Single-Fraction Spine Stereotactic Radiosurgery is Cost-Efficient

Key clinical point: A comparative cost analysis suggests single-fraction spine stereotactic radiosurgery is associated with lower total resource utilization among other radiation therapy (RT) options.

Major finding: Across the four RT regimens, full-cycle care costs for single-fraction spine stereotactic radiosurgery were 17% less and 17% more than intensity-modulated RT (IMRT) and three-dimensional conventional RT (3D-RT), respectively. Technical costs for IMRT were 50% and 77% more than 3-fraction and single-fraction SSRS, respectively.

Study details: A time-driven activity-based cost analysis of four RT prescriptions for spinal metastasis.

Disclosures: No funding sources were reported in the manuscript. The authors reported financial affiliations with AbbVie, AstraZeneca, Boston Scientific, Bristol-Myers Squibb BTG, Coleman Consulting, US Oncology, Oscar Health, RefleXion Medical, and several others.


Boyce-Fappiano D et al. J Oncol Pract. 2019 Nov 25. doi: 10.1200/JOP.19.00480.