Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Clinical Trials Unavailable for Most Cancer Patients

Key clinical point: Structural and clinical barriers make trial participation unachievable for more than three of four cancer patients.

Major finding: More than half (55.6%) of all cancer patients do not participate in trials because none are available for their cancer type and stage at the treating center.

Study details: A systematic review and meta-analysis of 13 cancer studies that documented the clinical trial decision-making process.

Disclosures: The study was supported by the National Cancer Institute. The authors reported no conflicts of interest.


Unger JM et al. J Natl Cancer Inst. 2019 Feb 19. doi: 10.1093/jnci/djy221.