Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Adding cannabinoids to opioids doesn’t improve cancer pain control

Key clinical point: Cannabinoids added to opioids did not reduce mean patient-reported pain scores.

Major finding: There was no significant difference in the mean difference in pain intensity between cannabinoids and placebo.

Study details: Systematic review and meta-analysis of five randomized controlled trials with 1,442 participants.

Disclosures: The authors did not report a funding source. No conflicts of interest were reported.


Boland EG et al. BMJ Supportive & Palliative Care 2020 Jan 20. doi: 10.1136/bmjspcare-2019-002032.