Clinical Edge

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Reduced SCC Risk With Higher Dietary Vitamin A Intake

Key clinical point: Higher intake of dietary vitamin A may reduce the risk of incident squamous cell carcinoma (SCC).

Major finding: Increased total vitamin A level was associated with a lower SCC risk (quintile 5 HR, 0.83; P less than .001 for trend).

Study details: A prospective cohort study of 3,978 SCC cases in 48,400 men and 75,170 women.

Disclosures: The study was funded by the National Institutes of Health and Inje University (South Korea).One author reported serving as a consultant for AbbVie, Amgen, the Centers for Disease Control and Prevention, Janssen, Merck, Novartis, and Pfizer, as well as a compensated investigator for Amgen, Regeneron, and Sanofi. The remaining four authors reported no disclosures.


Kim J et al. JAMA Dermatol. 2019 Jul 31. doi: 10.1001/jamadermatol.2019.1937.