Key clinical point: Treatment for low-grade pediatric tumors entails long-term cognitive and socioeconomic decrements.
Major finding: At follow-up, mean IQ was 93.9 for surgery plus radiotherapy, 101.2 for surgery alone, and 108.5 for unaffected siblings.
Study details: An examination of 286 participants in the Childhood Cancer Survivor Study.
Disclosures: The National Cancer Institute supported the study. The authors had no disclosures.
Ris MD et al. Cancer. 2019 Jun 24. doi: 10.1002/cncr.32186.
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Genomic characteristics of neuroblastomas linked with outcomes, Ackermann S et al. Science. 2018 Dec 7. doi: 10.1126/science.aat6768
Cochrane on Radiosurgery, Radiation for Brain Ca, Cochrane; 2017 Sep 25; Patil, Pricola, et al