Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Pregnancy does not increase melanoma recurrence risk
DiSano JA et al. J Surg Res. 2018 Jun 16. doi: 10.1016/j.jss.2018.05.026.
Key clinical point: Pregnancy after melanoma does not appear to increase risk for melanoma recurrence.
Major finding: The rate of pregnancy for women with melanoma was 15.8%, compared with 13.6% for controls (P less than .001).
Study details: A retrospective study of claims database records on 11,801 women with melanoma and an equal number of matched controls.
Disclosures: The study was supported by a Barsumian Trust grant; the authors reported having no conflicts of interest.
DiSano JA et al. J Surg Res. 2018 Jun 16. doi: 10.1016/j.jss.2018.05.026.
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Must Reads in Melanoma
Nivolumab boosts survival over chemo for advanced melanoma, Ascierto PA et al. JAMA Oncol. 2018 Oct 25. doi: 10.1001/jamaoncol.2018.4514
Checkpoint inhibitor combo continues to show benefit for advanced melanoma, Hodi FS et al. Lancet Oncol. 2018 Oct 22. doi: 10.1016/S1470-2045(18)30700-9
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Nivolumab plus ipilimumab ups survival in melanoma patients with brain mets, Tawbi HA et al. N Engl J Med. 2018 Aug 23. doi: 10.1056/NEJMoa1805453
Pregnancy does not increase melanoma recurrence risk, DiSano JA et al. J Surg Res. 2018 Jun 16. doi: 10.1016/j.jss.2018.05.026.