Clinical Edge

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HDAC/HMA combo shows ‘remarkable’ activity in PTCL

Key clinical point: Romidepsin and 5-azacytadine showed good activity in peripheral T-cell lymphomas (PTCL).

Major finding: In total, 11 of 16 patients with angioimmunoblastic T-cell lymphoma (AITL) or primary cutaneous follicular helper T-cell lymphoma (PTCL-TFH) had a clinical response.

Study details: A phase 2 open-label trial of 25 patients with PTCL.

Disclosures: Dr. Falchi reported having no financial disclosures. Other investigators reported funding from Celgene, which supported the study.


Falchi L et al. 15-ICML, Abstract 129.