Clinical Edge

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Pembrolizumab plus EP gives slight PFS edge in ES-SCLC

Key clinical point: Adding pembrolizumab to chemotherapy may improve outcomes in untreated extensive-stage small cell lung cancer.

Major finding: The median progression-free survival was 4.5 months with pembrolizumab and 4.3 months with placebo.

Study details: A randomized phase 3 trial of 453 patients with untreated extensive-stage small cell lung cancer.

Disclosures: Merck Sharp & Dohme supported the study. Dr. Rudin disclosed institutional research funding from Merck and a consulting or advisory role for other companies.

Citation:

Rudin CM et al. ASCO 2020. Abstract 9001.