Clinical Edge

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Neoantigen Vaccine Appears Safe and Active in NSCLC

Key clinical point: A personalized neoantigen vaccine appears safe and active in patients with non–small cell lung cancer.

Major finding: The neoantigen vaccine produced only grade 1 adverse events and yielded responses in seven patients, including one complete response.

Study details: Phase 1b trial of 24 patients with NSCLC.

Disclosures: The trial is sponsored by Tianjin Beichen Hospital and funded by Tianjin HengJia Biotechnology Development Co. Ltd. Dr. Lizee disclosed a consulting relationship with Tianjin HengJia Biotechnology Development Co. Ltd.

Citation:

Lizee G et al. SITC 2019. Abstract O18.