Clinical Edge

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Hurricanes Delay RT, Worsening Survival of NSCLC

Key clinical point: Hurricane-related disruptions in definitive radiotherapy for locally advanced NSCLC may compromise survival.

Major finding: Compared with nonexposed propensity-matched peers, patients exposed to a hurricane disaster declaration during their radiation treatment had poorer overall survival (adjusted hazard ratio for death, 1.19; P = .001).

Study details: Retrospective cohort study of 3,468 patients undergoing definitive radiotherapy for nonoperative locally advanced NSCLC during 2004-2014.

Disclosures: Dr. Nogueira disclosed no relevant conflicts of interest. The investigators conducted the study as part of the intramural research program at the American Cancer Society or contributed their time.


Nogueira LM et al. JAMA. 2019 Jul 16;322(3):269-71.