Clinical Edge

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Hurricanes Delay RT, Worsening Survival of NSCLC

Key clinical point: Hurricane-related disruptions in definitive radiotherapy for locally advanced NSCLC may compromise survival.

Major finding: Compared with nonexposed propensity-matched peers, patients exposed to a hurricane disaster declaration during their radiation treatment had poorer overall survival (adjusted hazard ratio for death, 1.19; P = .001).

Study details: Retrospective cohort study of 3,468 patients undergoing definitive radiotherapy for nonoperative locally advanced NSCLC during 2004-2014.

Disclosures: Dr. Nogueira disclosed no relevant conflicts of interest. The investigators conducted the study as part of the intramural research program at the American Cancer Society or contributed their time.

Citation:

Nogueira LM et al. JAMA. 2019 Jul 16;322(3):269-71.