Clinical Edge

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Variants in common genes linked to endometrial cancer risk

Key clinical point: Certain genetic variants may be linked to a greater risk of developing endometrial cancer.

Major finding: An analysis revealed 24 independent single-nucleotide polymorphisms that were associated with a higher risk of endometrial cancer.

Study details: A systematic review of 149 studies evaluating associations between genetic polymorphisms and endometrial cancer risk.

Disclosures: The National Institute for Health Research Manchester Biomedical Research Centre funded the study. The authors declared no conflicts of interest.


Bafligil C et al. J Med Genet. 2020 Feb 17. doi: 10.1136/jmedgenet-2019-106529.