Key clinical point: Investigators recommend considering genetic testing for Lynch syndrome in patients with endometrial cancer who have heterogeneous staining for DNA mismatch repair proteins.
Major finding: Three patients were found to have Lynch syndrome despite having immunohistochemical staining results that would have been reported as low risk.
Study details: Retrospective review of 455 patients who underwent hysterectomy for endometrial cancer.
Disclosures: The study was internally funded. Dr. Riedinger reported no conflicts of interest.
Riedeinger CJ et al. SGO 2020, Abstract 104.