Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Statins may affect prostate cancer microenvironment

Allott E et al. AUA 2018 (annual meeting of the American Urological Association), Abstract MP21-01.

Key clinical point: Researchers hope that genetic analyses could eventually point to prostate cancer patients who might benefit from statin use.

Major finding: Long-term statin users had lower odds of having a pTEN-null tumor (hazard ratio, 0.42), which is associated with worse outcomes.

Study details: Retrospective analysis of 5,792 diagnoses of prostate cancer among 44,076 men.

Disclosures: The study was funded by the Irish Cancer Society, the John Fitzpatrick Fellowship, and the National Cancer Institute. Dr. Allott reported no relevant financial relationships.

Source: Allott E et al. AUA 2018, Abstract MP21-01.

Citation:

Allott E et al. AUA 2018 (annual meeting of the American Urological Association), Abstract MP21-01.

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