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Predicting complications of cytoreductive nephrectomy in metastatic RCC

Key clinical point: Patients with higher intraoperative blood loss and those treated at lower-volume surgical centers had a greater risk of high-grade complications after undergoing cytoreductive nephrectomy for metastatic renal cell carcinoma (RCC).

Major finding: The odds ratio for high-grade postoperative complications per 200 mL of blood lost was 1.06 (P = .007). The odds ratio for high-grade complications per 25 cases treated was 0.88 (P = .04).

Methods: Analysis of registry data from 736 patients with metastatic RCC who underwent cytoreductive nephrectomy at 14 centers during 1980-2019.

Disclosures: There was no external funding for this research, and the investigators didn’t have any disclosures.


Roussel E et al. Eur Urol Oncol. 2020 Aug;3(4):523-9.