Clinical Edge

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Large waistline linked to higher risk of prostate cancer death

Key clinical point: Central adiposity appeared to increase the risk of death from prostate cancer by more than 30% during a 10.8-year observation period.

Major finding: In a comparison of men in the highest to lowest quartiles of waist circumference and waist-to-hip ratio, the hazard ratios for prostate cancer death were a respective 1.35 and 1.34. Body mass index and total adiposity were not linked to prostate cancer deaths.

Study details: An observational study of 218,255 men from the UK Biobank study, 571 of whom died from prostate cancer over a 10.8-year follow-up period.

Disclosures: The study was supported by a grant from Cancer Research UK. The study’s authors had no conflicts of interest.


Pérez-Cornago A et al. ECOICO 2020. LBP-075.