Clinical Edge

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Large study probes colonoscopy surveillance intervals

Key clinical point: High-risk adenomas, but not low-risk adenomas, are associated with increased long-term risks of colorectal cancer (CRC) and CRC-related death.

Major finding: Compared with patients without adenomas, patients diagnosed with high-risk adenoma had a significantly increased risk of colorectal cancer (hazard ratio, 2.61).

Study details: A retrospective cohort study involving 64,422 patients who underwent colonoscopy between 2004 and 2010.

Disclosures: The study was supported by the National Cancer Institute and the American Gastroenterological Association. The investigators disclosed no conflicts of interest.


Lee JK et al. Gastroenterology. 2019 Oct 4. doi: 10.1053/j.gastro.2019.09.039.