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INR fails to predict bleeding in patients with cirrhosis

Key clinical point: International normalized ratio (INR) does not predict periprocedural bleeding in patients with cirrhosis.

Major finding: Preprocedural INR was not significantly associated with periprocedural bleeding events (pooled odds ratio, 1.52; 95% confidence 0.99-2.33; P = .06).

Study details: A systemic review and meta-analysis involving 13,276 patients with cirrhosis.

Disclosures: The investigators disclosed relationships with AbbVie, Eisai, Gilead, and others.


Kovalic AJ et al. Aliment Pharmacol Ther. 2020 Sep 10. doi: 10.1111/apt.16078.