Clinical Edge

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Rituximab Appears to Lower Risk of Late Relapse in DLBCL

Key clinical point: Frontline rituximab can lower the risk of late relapse in patients with diffuse large B-cell lymphoma (DLBCL).

Major finding: Patients who received frontline treatment with rituximab had a lower risk of late relapse (P less than .001), compared with patients who did not receive rituximab upfront.

Study details: Retrospective study of 1,113 DLBCL patients.

Disclosures: The authors reported relationships with Celgene, Roche, Janssen, MEI Pharma, Astra Zeneca, Celltrion Healthcare, AbbVie, Gilead, Takeda, Sunesis, Morphosys, and Sanofi.


Vannata B et al. Br J Haematol. 2019 Aug 5. doi: 10.1111/bjh.16106.