Clinical Edge

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COVID-19 in China: Children have less severe disease, but are vulnerable

Key clinical point: Clinical manifestations of COVID-19 have been less severe in children than in adults. Nonetheless, children of all ages – and infants in particular – are vulnerable to novel coronavirus 2019 infection.

Major finding: The proportion of severe and critical cases was 11% for infants under 1 year of age, compared with 7% for those aged 1-5 years; 4% for those aged 6-10 years; 4% for those 11-15 years; and 3% for those 16 years and older.

Study details: A review of 2,143 pediatric COVID-19 cases in China.

Disclosures: This study was partially supported by the Science and Technology Commission of Shanghai Municipality. The authors reported having no disclosures. Dr. Cruz and Dr. Zeichner are associate editors for Pediatrics. Dr. Cruz reported having no disclosures. Dr. Zeichner is an inventor of new technologies for the rapid production of vaccines, for which the University of Virginia has filed patent applications.