Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

COPD Adds Complexity to Shared Decision Making for LDCT Lung Cancer Screening

Key clinical point. Conditions such as COPD can impact the risk-benefit balance for low-dose CT screening for lung cancer.

Major finding: Patients with COPD had a significantly higher incidence of lung cancer diagnosis than did participants without COPD (6.1% vs. 3.6%).

Study details: Secondary analysis of patient-level outcomes from 75,138 low-dose computed tomography scans in 26,453 participants.

Disclosures: The study was supported by the American Society of Clinical Oncology, the Charles A. King Trust, and Edith Nourse Rogers Memorial Veterans Hospital. No conflicts of interest were declared.


Iaccarino J et al. Chest 2019 Jul 5. doi: 10.1016/j.chest.2019.06.016.