Clinical Edge

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Late effects in young cancer survivors underscore importance of high-risk screening

Key clinical point: Adolescent and young adult cancer survivors have higher standardized mortality ratios than the general population but lower ratios than childhood cancer survivors.

Major finding: The standardized mortality ratios for all-cause mortality among 5,804 adolescent and young adult survivors and 5,804 diagnosis-matched children versus the general population were 5.9 and 6.2, respectively.

Study details: An analysis of data from more than 11,600 individuals in the retrospective Childhood Cancer Survivor Study cohort.

Disclosures: The study was funded by the National Cancer Institute and American Lebanese-Syrian Associated Charities. The authors reported having no competing interests.


Suh E et al. Lancet Oncol. 2020 Feb 14. doi: 10.1016/S1470-2045(19)30800-9.