Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Ultrasound method predicts liver complications in pediatric transplant

Key clinical point: Shear wave elastography (SWE) might be useful for predicting which pediatric patients will develop severe hepatic sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD).

Major finding: Increased SWE velocity predicted severe SOS/VOD, with a cutoff value of 1.65 m/s being 92% sensitive and 67% specific for the complication.

Study details: A prospective, two-center study including 54 pediatric patients who underwent hematopoietic stem cell transplantation.

Disclosures: Dr. Chan reported consulting for Jazz Pharmaceuticals.


Chan SS et al. TCT 2019, Abstract 55.