Clinical Edge

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Ten years of anastrozole boosts disease-free survival

Ohtani S et al. SABCS 2018, Abstract GS3-04

Key clinical point: Extending treatment with adjuvant anastrozole to 10 years improves disease free survival and distant DFS in HR+ breast cancer.

Major finding: DFS was 91.9% in patients who continued anastrozole versus 84.4% in those who stopped anastrozole after the initial 5 years (hazard ratio, 0.548; P = .0004).

Study details: A prospective, randomized, open-label, phase 3 study of 1,683 patients.

Disclosures: Dr. Ohtani has received speaker fees from CHUGAI, Astra Zeneca, Novartis, and Ezai.

Read the aerticle here.


Ohtani S et al. SABCS 2018, Abstract GS3-04.