Key clinical point: Cancer type, stage, and recent treatment may affect outcomes of COVID-19 in cancer patients.
Major finding: Compared to patients without cancer, those with metastatic cancer had a higher risk of severe/critical COVID-19 symptoms (odds ratio, 5.97; P < .01), ICU admission (OR, 6.59; P < .01), invasive mechanical ventilation (OR, 55.42; P < .01), and death (OR, 5.58; P = .01).
Study details: Multicenter study of 105 cancer patients and 536 noncancer patients, all with COVID-19.
Disclosures: The study was supported by the National Natural Science Foundation of China, the Singapore Ministry of Health’s National Medical Research Council, the National Institutes of Health/National Heart, Lung, and Blood Institute, and the Xiu Research Fund. Dr. Cai said she has no conflicts of interest.
Cai H. AACR 2020. Patients with cancer appear more vulnerable to SARS-COV-2: A multicenter study during the COVID-19 outbreak; Dai M et al. Cancer Discov. 2020 Apr 28. doi: 10.1158/2159-8290.CD-20-0422.