Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Diet, Exercise Don’t Improve Breast Cancer-related Lymphedema

Key clinical point: Exercise and weight loss did not affect lymphedema outcomes in overweight women.

Major finding: There were no significant between-group differences in percentage of or absolute limb-volume difference.

Study details: A randomized prospective trial in 351 women with breast cancer–related lymphedema.

Disclosures: The study was supported by various National Institutes of Health grants. Compression garments were supplied by BSN Medical. Dr. Schmitz reported receiving grants from the National Cancer Institute and nonfinancial support from BSN Medical during the conduct of the study, personal fees from Klose Training outside the submitted work, and a licensed patent for a Strength After Breast Cancer course.


Schmitz KH et al. JAMA Oncol. 2019 Aug 15. doi: 10.1001/jamaoncol.2019.2109.