Clinical Edge

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CVD Risk After Breast Cancer: Adipose Distribution Trumps BMI

Key clinical point: Greater visceral or intramuscular adiposity, even in the face of normal BMI, increases breast cancer survivors’ CVD risk.

Major finding: CVD risk rose by 15% with each SD in visceral adiposity and by 21% with each SD in intramuscular adiposity.

Study details: Retrospective cohort study of 2,943 patients with nonmetastatic breast cancer having a median follow-up of 6 years.

Disclosures: Dr. Cespedes Feliciano disclosed no relevant conflicts of interest. The study did not receive any specific funding.


Cespedes Feliciano EM et al. J Clin Oncol. 2019 Aug 1. doi: 10.1200/JCO.19.00286.