Key clinical point: Platelet counts less than 150,000/mm3 were more common in complicated pregnancies.
Major finding: Platelet counts were below 150,000/mm3 in 11.9% of complicated versus 9.9% of uncomplicated pregnancies at the time of delivery (P = .01).
Study details: Review of records of 7,351 pregnant women delivering at a single site, compared with NHANES data for 8,885 nonpregnant women.
Disclosures: The National Institutes of Health funded the study. The authors reported having no conflicts of interest.
Source: Reese J et al. N Engl J Med. 2018;379:32-43.
Reese J et al. N Engl J Med. 2018;379:32-43.
This Week's Must Reads
Case studies shed light on treatment for rare form of MCL , Mori S et al. Clin Lymphoma Myeloma Leuk. 2019 Feb;19(2):e93-7.
Histopathological clues for differentiating follicular lymphomas, Servitje O et al. J Cutan Pathol. 2019;46:182-9.
Single agent daratumumab is not an option in B-cell lymphomas, Salles G et al. Clin Lymphoma Myeloma Leuk. 2019 Jan 2. doi: 10.1016/j.clml.2018.12.013.
Ibrutinib combo advances in CNS lymphoma, Grommes C et al. Blood. 2019;133(5):436-45.
Best frontline options for advanced follicular lymphoma, Shah NN et al. Clin Lymphoma Myeloma Leuk. 2019 Feb;19(2):95-102.
Must Reads in Bleeding Disorders
Durable responses for hemophilia A gene therapy, High K et al. ASH 2018, Abstract 487
A clot lysis contradiction with mild bleeding, Vries MJA et al. Thromb Res. 2018 Dec 4. doi: 10.1016/j.thromres.2018.12.004
Factor VIII inhibitors seen in some patient subgroups, not others, Gangadharan B et al. ASH 2018, Poster 3774
Could thrombin generation be a better biomarker?, Nossair F et al. ASH 2018, Poster 3788
Novoeight looks safe in hemophilia A extension trial, Lentz SR et al. Haemophilia. 2018 Nov;24(6):e391-e394