Clinical Edge

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Osteoporotic Fracture Risk Appears Higher in Adults with Hemophilia

Key clinical point: A nationwide study has found that the risk of developing osteoporotic fractures may be higher in patients with hemophilia.

Major finding: After adjusting for covariates, patients with hemophilia had a significantly higher risk of developing osteoporotic fractures versus matched controls (overall adjusted hazard ratio, 4.37; 95% confidence interval, 1.88-10.17; P = .001).

Study details: A population‐based cohort study of 75 patients with hemophilia and 300 control subjects.

Disclosures: No funding sources were reported. The authors reported having no conflicts of interest.


Tuan S-H et al. Haemophilia. 2019 Jul 7. doi: 10.1111/hae.13814.