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Lower BMD Found in Patients With Severe Hemophilia A

Key clinical point: Patients with severe hemophilia A have reduced levels of bone mineral density, compared with the general population.

Major finding: Decrease in bone mineral density was significantly greater in patients with severe hemophilia A than in the normal healthy population for femoral neck and total hip bone mineral density (P = .017 and P less than .001, respectively), but not for lumbar spine bone mineral density (P = .071).

Study details: A case-control study of 41 men with severe hemophilia A and 40 controls without hemophilia A.

Disclosures: The study was funded by the Yüzüncü Yıl University Scientific Research Project Committee. The authors reported no conflicts of interest.


Ekinci O et al. Haemophilia. 2019 Aug 8. doi: 10.1111/hae.13836.