Key clinical point: More frequent monitoring of kidney function might be considered for patients on warfarin with an INR of 4.0 or greater.
Major finding: Among patients with warfarin anticoagulation, 13% had an acute kidney injury.
Study details: A retrospective study of 292 patients with an INR of 4.0 or greater who were treated between 2007 and 2017.
Disclosures: Dr. Traquair reported having no financial disclosures.
Source: Traquair H et al. THSNA 2018, Poster 79.
Traquair H et al. biennial summit of the Thrombosis & Hemostasis Societies of North America 2018, Poster 79.
This Week's Must Reads
Intensity modulated radiation therapy may be preferable in children with extremity nonrhabdomyosarcoma soft-tissue sarcomas, Source: Rao A et al. Intl J Rad Oncology*Biology*Physics; Jan. 2019, 38-44. https://doi.org/10.1016/j.ijrobp.2018.09.005
TAO: Nonwhite ethnicity, limb infection predict poor prognosis, Le Joncour A et al. Arthritis Rheumatol. 2018;70(Suppl 10): Abstract 1885
Thrombolysis for acute ischemic stroke safe in GI malignancy, Inohara T et al. Circulation. 2018 Nov 6;138[suppl 1], Abstract A12291
Ten years of anastrozole boosts disease-free survival, Ohtani S et al. SABCS 2018, Abstract GS3-04
Outcomes better in TNBC with adjuvant chemotherapy within 30 days of surgery, Morante Z et al., SABCS 2018 Abstract GS2-05
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FDA draft guidance on platelet safety, FDA Draft Guidance, December 2018
HemoTypeSC offers rapid sickle cell detection, Serrao E et al. ASH 2018, Abstract LBA-3
Impact of RBC transfusion limits, Roubinian NH et al. Ann Intern Med. 2018 Dec 18. doi: 10.7326/M17-3253
Early results for novel hemophilia A infusion, Chowdary P et al. ASH 2018, Abstract 489
Diagnostic challenges in hemophilia A, Patil R et al. Thromb Res. 2018 Dec;172:29-35