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GI Bleed Risk Factors in von Willebrand Disease Identified

Key clinical point: Researchers identified several risk factors associated for gastrointestinal bleeding in adult patients with von Willebrand disease.

Major finding: In a multivariate analysis, the most significant factors associated with gastrointestinal bleeding in von Willebrand disease were smoking status, African American race, male gender, angiodysplasia, diverticulitis, and hepatitis C.

Study details: A retrospective analysis of 16,640 patients with the disease.

Disclosures: The Pennsylvania Department of Health and the Health Resources and Services Administration funded the study. The authors reported having no conflicts of interest.


Tsagianni A et al. Thromb Res. 2019 Apr 17. doi: 10.1016/j.thromres.2019.04.017