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FXIII Replacement May Improve Hemostasis in Acquired Hemophilia A

Key clinical point: Measuring Factor XIII levels may be useful in acquired hemophilia A patients with refractory bleeding.

Major finding: Among seven patients admitted to the hospital for acquired hemophilia A, FXIII antigen was measured in five patients. FXIII was low in four patients and FXIII replacement was required in three patients to secure hemostasis.

Study details: Retrospective case series of seven patients with acquired hemophilia A.

Disclosures: No funding sources were reported. The authors reported having no conflicts of interest.


Abdulrehman J et al. Haemophilia. 2019 Mar 7. doi: 10.1111/hae.13690.