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A clot lysis contradiction with mild bleeding

Vries MJA et al. Thromb Res. 2018 Dec 4. doi: 10.1016/j.thromres.2018.12.004

Key clinical point: Patients with self-reported mild bleeding symptoms may have impaired clot lysis, in contrast with known bleeding disorders.

Major finding: Patients with mild bleeding had longer whole blood tissue plasminogen activator-rotational thromboelastometry lysis times (P = .022) than did patients without symptoms.

Study details: An observational study of 335 adult patients undergoing elective surgery.

Disclosures: This study was funded by the Sint Annadal Foundation, Maastricht University Medical Center, CTMM INCOAG Maastricht, Cardiovascular Research Institute Maastricht, and the British Heart Foundation. No conflicts of interest were reported.

Read the article here.


Vries MJA et al. Thromb Res. 2018 Dec 4. doi: 10.1016/j.thromres.2018.12.004.