Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

SOX11 Shows Value as Diagnostic Marker in MCL

Key clinical point: A meta-analysis suggests SOX11 may be an accurate diagnostic marker for mantle cell lymphoma (MCL), distinguishing it from other lymphoproliferative disorders.

Major finding: The pooled specificity and sensitivity were 0.95 and 0.9, respectively.

Study details: A meta-analysis of 14 published case-control studies.

Disclosures: The study was funded by the Next-Generation BioGreen 21 program (Republic of Korea). The authors reported having no conflicts of interest.


Lee W et al. PLoS One. 2019 Nov 12. doi: 10.1371/journal.pone.0225096.