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Case studies shed light on treatment for rare form of MCL

Mori S et al. Clin Lymphoma Myeloma Leuk. 2019 Feb;19(2):e93-7.

Key clinical point: Aggressive leukemic nonnodal mantle cell lymphoma (L-NN-MCL) may be highly responsive to combination therapy with rituximab and ibrutinib.

Major finding: Two patients with aggressive L-NN-MCL and P53 abnormalities who were treated with rituximab/ibrutinib and autologous stem cell transplantation remain free of disease 18 months later.

Study details: Two case reports.

Disclosures: The authors reported having no financial disclosures.

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Citation:

Mori S et al. Clin Lymphoma Myeloma Leuk. 2019 Feb;19(2):e93-7.