Clinical Edge

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AFib patients do best on a DOAC started 7-10 days post stroke

Key clinical point: A direct-acting oral anticoagulant begun 7-10 days after a stroke produced the best outcome, but just missed statistical significance.

Major finding: Patients starting a DOAC 7-10 days after an index stroke experienced half the number of events of other patients.

Study details: Review of 1,289 patients with atrial fibrillation managed and followed after a cardioembolic stroke at any of eight U.S. stroke centers.

Disclosures: Dr. Yaghi disclosed a financial relationship with Medtronic. Dr. Simpkins had no disclosures.


Yaghi S et al. Stroke. 2020 Feb;51(suppl 1):A119.