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Low plasma sodium levels can predict complications in acute painful episodes of SCD

Key clinical point: Low plasma sodium concentrations are associated with the incidence of acute chest syndrome.

Major finding: Plasma sodium concentration ≤ 135 mmol/L at hospital admission predicts complications in initially uncomplicated sickle cell acute painful episodes.

Study details: A single-center database study of 1,218 stays (406 patients) for SCD painful episodes.

Disclosures: The authors declared that they had no conflicts and that there was no funding source.


Rech JS et al. Am J Med. 2020 Mar 18;