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Flow-mediated dilation of brachial artery predicts renal dysfunction in sickle cell disease

Key clinical point: Sonographic flow-mediated dilation (FMD) of the brachial artery may predict renal dysfunction in patients with sickle cell disease (SCD).

Major finding: Flow-mediated dilation (FMD) was negatively correlated with serum level of cystatin C (P = .013).

Study details: A cross-sectional comparative study involving 44 patients with homozygous SCD and 33 age- and sex-matched controls.

Disclosures: The study was funded by the Obafemi Awolowo University Teaching Hospital. The investigators reported no conflicts of interest.


Ayoola et al. Kidney360. 2020 Jan 30. doi: 10.34067/KID.0000142019.