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T cell infusion effective in PML

Muftuoglu M et al. N Engl J Med. 2018 Oct 11;379:1443-51

Key clinical point: Infusion of allogeneic BK virus-specific T cells may be an effective treatment for patients with PML.

Major finding: Two of three patients cleared JC virus from cerebrospinal fluid after infusion.

Study details: A case series involving three patients with PML.

Disclosures: The study was funded by the MD Anderson Cancer Center Moon Shots Program and the National Institutes of Health.

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Citation:

Muftuoglu M et al. N Engl J Med. 2018 Oct 11;379:1443-51