Major advances in the understanding of breast cancer biology have led to new treatment options that have dramatically improved the prognosis for breast cancer patients in the past few decades. Yet, breast cancer remains a significant health problem; in 2011 it was estimated that about 2.9 million women were living with breast cancer in the United States and median survival in the metastatic setting is only 2 years. Thus, the development of new and effective treatment options remains a priority. Here, we discuss the most significant advances in recent years that are changing oncology practice today and for the future.
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